If the “Save”-button on map or marker edit pages is disabled and cannot be clicked, it is likely that this is caused by a plugin conflict. To verify this, please disable all other plugins but Maps Marker Pro and try again. If it works afterwards, please enable all other plugins one by one again to find out which plugin is causing this issue and let us know in a support ticket which plugin so that we can check if we can fix this from our side.
If this does not help, it is likely that there might be an issue with your general WordPress AJAX endpoint. Have a look into the browser console (can be opened with key F11 for example) to see if there are any error messages. Send us these error messages in a support ticket so that we can have a closer look.